1. Inhibitory Antibodies
  2. Atibuclimab

Atibuclimab  (Synonyms: 阿替布利单抗)

目录号: HY-P99008 纯度: 97.74%
COA

Atibuclimab 是一种针对 CD14 的嵌合单克隆抗体,由小鼠可变区和人类 IgG4 Fc 区组成。Atibuclimab 可用于肌萎缩侧索硬化症的研究。Atibuclimab 可减轻 LPS 诱导的症状,并强烈抑制 LPS 诱导的促炎细胞因子释放,同时仅延迟抗炎细胞因子可溶性 TNF 受体 I 型和 IL-1 受体拮抗剂的释放。

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CAS No. : 2417175-94-9

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规格 价格 是否有货 数量
1 mg ¥2000
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5 mg ¥5600
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10 mg ¥8500
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MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Atibuclimab, is a chimeric monoclonal antibody directed against CD14 and is composed of murine variable and human IgG4 Fc regions. Atibuclimab can be used for the research of amyotrophic lateral sclerosis[1]. Atibuclimab attenuates LPS-induced symptoms and strongly inhibits LPS-induced proinflammatory cytokine release, while only delaying the release of the anti-inflammatory cytokines soluble TNF receptor type I and IL-1 receptor antagonist[2].

同型

Human IgG4 kappa

推荐同型对照抗体
种属

Chimeric

CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

阿替布利单抗

运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • Human IgG4 kappa
纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Atibuclimab
目录号:
HY-P99008
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